Journal: International Journal of Molecular Sciences
Article Title: Imbalanced IL-1B and IL-18 Expression in Sézary Syndrome
doi: 10.3390/ijms24054674
Figure Lengend Snippet: Decreased IL-1B expression and IL-18 upregulation in lymph nodes at an advanced stage of SS. The expressions of IL-1B and IL-18 were assessed in the lymph-node biopsies of SS patients at stages N1 ( n = 4, open circle), N2 ( n = 2, pink circle), and N3 ( n = 2, closed circle), as well as in idiopathic erythroderma patients (IE, n = 8, open triangle), by immunohistochemistry. ( A ) Representative images, original magnification ×20. ( B ) IL-1B expression and IL-18 expression. Data are illustrated by median values. * p ≤ 0.05.
Article Snippet: The tissue sections were then incubated with the primary antibodies polyclonal anti-NLRP1 rabbit antibody (Ab 3683); monoclonal mice anti-NLRP3 (214185); polyclonal anti-AIM2 rabbit antibody (93015); polyclonal anti-IL-18 rabbit antibody (Ab71495); and polyclonal anti-IL-1B rabbit antibody (Ab2105), all of which were from Abcam (Cambridge, MA, USA).
Techniques: Expressing, Immunohistochemistry